Mission: The Cosmetic Ingredient Review thoroughly reviews and assesses the safety of ingredients used in cosmetics in an open, unbiased, and expert manner, and publishes the results in the peer-reviewed scientific literature.

111^thCIR Expert Panel Meeting

The meeting Agenda was last updated 11/16/09.

The meeting Results were last updated 12/16/09.

The First Thirty Years

1975		- FDA labeling regulation requires safety substantiation or warning on cosmetic product labels
1976		- CIR established by CTFA Board of Directors to assess ingredient safety - CIR steering committee members include Jim Merritt, Bob Giovacchini, Norm Estrin, Joe Borzelleca, and Richard Dobson - Edward Burger appointed first CIR Director
1977		- CIR Steering Committee appoints Expert Panel - Ralph Wands appointed CIR Scientific Coordinator - Review priorities developed
1978		- Ralph Wands becomes second CIR Director - Jack Winstead serves as Industry Liaison to the Panel, replacing James McNerney
1979		- Robert Elder appointed third CIR Director - National Association of Professional Insurance Agents presents its Consumer Product Safety Award to CTFA for its CIR program. - Cathy Sulzberger, Kathleen Sheekey and Marcia Carroll each serve briefly, then Anne Averyt appointed as Consumer Liaison to the Panel - 3 safety assessments on 12 ingredients
1980		- Arnold Schroeter replaces Robert Fine on Expert Panel - James McNerney again serves as industry liaison, replacing Jack Winstead - Review priorities revised - 18 safety assessments covering 67 ingredients
1981		- John Wenninger and then Heinz Eiermann replace Martin Grief as FDA Liaison to the Panel - 14 safety assessments covering 45 ingredients
1982		- Roswell Boutwell, Jerry Hook, and William Carlton replace Robert Roudabush, Julius Coon, and William Montagna on the Panel; William Jordan replaces Richard Dobson on the CIR Steering Committee representing the Academy of Dermatology - Jerry McEwen becomes industry liaison to the Panel, replacing James McNerney - 6 safety assessments on 13 ingredients
1983		- William Berndt replaces Jerry Hook as Panel member - 23 safety assessments on 80 ingredients
1984		- Ronald Shank replaces Roswell Boutwell as Panel member - Mary Ellen Fise replaces Anne Averyt as Consumer Liaison - Review priorities revised - 9 safety assessments on 22 ingredients
1985		- 15 safety assessments on 27 ingredients
1986		- CIR celebrates 10th anniversary - 9 safety assessments on 22 ingredients
1987		- Karl Beyer leaves the Panel; William Berndt elevated to position of Chair; Roswell Boutwell reappointed as Panel member - 14 safety assessments on 34 ingredients
1988		- Wyden Hearings on cosmetic product safety - 8 safety assessments on 10 ingredients
1989		- 15 safety assessments on 21 ingredients
1990		- 13 safety assessments on 15 ingredients
1991		- William Berndt retires; Wilma Bergfeld appointed as new Chair; Don Belsito joins the Panel. - John Bailey becomes FDA liaison to the Expert Panel - 6 safety assessments on 8 ingredients
1992		- 22 safety assessments on 40 ingredients
1993		- Roswell Boutwell and Dietrich Hoffman leave the Panel; Tom Slaga and Curt Klaassen fill vacancies. - Alan Andersen appointed as fourth CIR Director - 14 safety assessments on 19 ingredients
1994		- CIR celebrates 50th CIR Expert Panel meeting - Panel agrees to expedite review of Alpha Hydroxy Acids - For the first time, CIR reports appear in three issues of the Journal of the American College of Toxicology - 26 safety assessments on 30 ingredients
1995		- 15 safety assessments on 32 ingredients
1996		- CIR celebrates 20th anniversary - 19 safety assessments on 153 ingredients
1997		- Journal of the American College of Toxicology becomes the International Journal of Toxicology - 21 safety assessments on 115 ingredients
1998		- 23 safety assessments on 132 ingredients
1999		- Team meetings opened to public - Panel rotation begins - Paul Snyder replaces Bill Carlton as Panel member - Adele Dennis replaces John Bailey as FDA liaison - 17 safety assessments on 121 ingredients
2000		- CIR receives Gold Triangle Award from the American Academy of Dermatology - Expert Panel holds 75th meeting - 13 safety assessments on 146 ingredients
2001		- Jim Marks replaces Arnold Schroeter as Panel member and team leader - Expert Panel begins re-review process - CIR celebrates 25th anniversary - September 11 terrorist attacks cuts short CIR Expert Panel meeting - Ella Toombs replaces Adele Dennis as FDA liaison at the end of the year - 11 safety assessments on 111 ingredients - 39 ingredients re-reviewed
2002		- Rachel Weintraub replaces Mary Ellen Fise as the Consumer Federation of America liaison - Linda Katz replaces Ella Toombs as the FDA liaison - 7 safety assessments on 46 ingredients - 49 ingredients re-reviewed
2003		- Hair dye epidemiology data updated - 6 safety assessments on 37 ingredients - 84 ingredients re-reviewed
2004		- Environmental Working Group provides data on ingredient usage - Paul Foster from NIEHS reviews data on endocrine-active chemicals - 7 safety assessments on 20 ingredients - 27 ingredients re-reviewed - propyl gallate and parabens safety assessments reopened
2005		- Pamela G. Bailey replaces Ed Kavanaugh as CTFA President and CEO - 11 safety assessments on 99 ingredients - 25 ingredients re-reviewed - n-Butyl Alcohol and cyclomethicones safety assessment reopened
2006		- FDA celebrates centennial of 1906 Pure Food and Drugs Act - CTFA announces intent to strengthen and enhance CIR program - John Bailey replaces Jerry McEwen as industry liaison - CIR Director, Alan Andersen, receives FDA Distinguished Alumni Award - CIR celebrates 30th anniversary — holds 100th CIR Expert Panel meeting

781 ingredients safe as used

408 ingredients safe with qualifications

119 ingredients with insufficient data

9 ingredients unsafe

Total of 1298 ingredients reviewed through August 2006.